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Introduction to PBPK modeling in R with mrgsolve

  • CIC Cambridge (101 Main St. Location) - Cloud City, 14th floor 101 Main Street Cambridge, MA, 02142 United States (map)

Introduction to PBPK modeling in R with mrgsolve

This 1.5 day hands-on workshop will provide participants with a technical foundation for physiologically-based pharmacokinetic (PBPK) model development in R using mrgsolve, a free, open-source modeling and simulation platform for ODE-based model development in R (https://mrgsolve.github.io).

The workshop gets started with an introduction to simulation with mrgsolve. We'll cover the essentials of a tidy simulation workflow in R. Then we'll jump into PBPK modeling with mrgsolve. After a brief introduction to principles of PBPK, we'll work through case studies using PBPK modeling. The case studies use published models focused on problems like drug-drug interactions and exploring pharmacokinetics in special populations. Finally, we will introduce tools and workflows in R to help you accomplish modeling tasks such as sensitivity analysis and parameter estimation.

For more information on pre-requesistes for attendees, materials provided, and to reserve your slot, visit the event page! Note: this is a two-day workshop on June 6th and 7th.

CICers receive a 25% discount from the industry price below using code "CICMember"!

Cost:
$1500 Industry
$750 Academia/Gov/Non-Profit
$150 Student